CovidV2, an2020, Analysis, bibRecord, 000601

Liver injury during highly pathogenic human coronavirus infections.

Identifieur interne : 000601 ( an2020/Analysis ); précédent : 000600; suivant : 000602

Liver injury during highly pathogenic human coronavirus infections.

Auteurs : Ling Xu [République populaire de Chine] ; Jia Liu [République populaire de Chine] ; Mengji Lu [Allemagne] ; Dongliang Yang [République populaire de Chine] ; Xin Zheng [République populaire de Chine]

Source :

Liver international : official journal of the International Association for the Study of the Liver [ 1478-3231 ] ; 2020.

RBID : pubmed:32170806

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), the pathogen of 2019 novel coronavirus disease (COVID-19), has posed a serious threat to global public health. The WHO has declared the outbreak of SARS-CoV-2 infection an international public health emergency. Lung lesions have been considered as the major damage caused by SARS-CoV-2 infection. However, liver injury has also been reported to occur during the course of the disease in severe cases. Similarly, previous studies have shown that liver damage was common in the patients infected by the other two highly pathogenic coronavirus - severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV), and associated with the severity of diseases. In this review, the characteristics and mechanism of liver injury caused by SARS-CoV, MERS-CoV, as well as SARS-CoV-2 infection were summarized, which may provide help for further studies on the liver injury of COVID-19.

DOI: 10.1111/liv.14435
PubMed: 32170806

Affiliations:

Allemagne, République populaire de Chine

Links to Exploration step

pubmed:32170806

Le document en format XML

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<front><div type="abstract" xml:lang="en">The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), the pathogen of 2019 novel coronavirus disease (COVID-19), has posed a serious threat to global public health. The WHO has declared the outbreak of SARS-CoV-2 infection an international public health emergency. Lung lesions have been considered as the major damage caused by SARS-CoV-2 infection. However, liver injury has also been reported to occur during the course of the disease in severe cases. Similarly, previous studies have shown that liver damage was common in the patients infected by the other two highly pathogenic coronavirus - severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV), and associated with the severity of diseases. In this review, the characteristics and mechanism of liver injury caused by SARS-CoV, MERS-CoV, as well as SARS-CoV-2 infection were summarized, which may provide help for further studies on the liver injury of COVID-19.</div>
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Liver injury during highly pathogenic human coronavirus infections.

Liver injury during highly pathogenic human coronavirus infections.

Source :

Abstract

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Links to Exploration step

Le document en format XML

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